The Tanzania HIV Impact Survey (THIS 2022-2023) is a household-based national survey among adults of age 15 years and older that measure the impact of the country’s national and regional HIV response. The Government of the United Republic of Tanzania through the Tanzania Commission for AIDS (TACAIDS), the Zanzibar AIDS Commission (ZAC), and the Ministries of Health of the United Republic of Tanzania and the Revolutionary Government of Zanzibar led THIS 2022-2023. The National Bureau of Statistics (NBS), the Office of Chief Government Statistician (OCGS) in Zanzibar, implemented THIS 2022-2023 with technical assistance from the US Centers for Disease Control and Prevention (CDC) and ICAP at Columbia University.